After poisoning his wife, local gangster Bisman blames her death on the village cleric and instigates an outraged mob to burn down his hut, killing him in the process. The cleric’s wife Katemi escapes into the jungle, eventually meeting Nyi Angker, a half-crocodile half-witch who gives Katemi diabolical powers, thus allowing her to commence a bloody revenge.

Katemi, shunned for past murders, is cursed by Nyi Angker's mentor, transforming her into a vicious tiger each night, brutally slaughtering villagers. Madness ensues as Katemi's nightly rampages continue, ripping people limb from limb.